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New computational pipeline revolutionizes personalized cancer vaccine design

Ludwig Cancer Research scientists have developed a full, start-to-finish computational pipeline that integrates multiple molecular and genetic analyses of tumors and the specific molecular...

Fishing for proteins: Scientists use new optical tweezer technology to study DNA repair

Tucked away in a small, dark room at UPMC Hillman Cancer Center, Brittani Schnable is on a fishing expedition. Credit: Schaich et al., 2023, Nucleic...

Insilico Details AI-Designed, Cancer-Fighting PROTAC Targeting PKMYT1

Because of its pivotal role in cell cycle regulation—and its overexpression in various types of cancer—membrane-associated tyrosine-threonine protein kinase 1 (PKMYT1) has emerged as...

Visualizing lipid transport inside living cells with fluorescence microscopy

To the point: New technique to image single lipids: Lipids are notoriously difficult to detect with light microscopy. Using a new chemical labeling strategy,...

“One-Pot,” Fluorescence-Based COVID-19 Test is Quick and Easy

Experts have agreed, for some time now, that the United States needs better COVID-19  testing. Eight months after SARS-CoV-2 virus first entered the country,...

Researchers develop the world’s first digital cancer cell model

The computer model, developed under the lead management of researchers at TU Graz, simulates the cyclical changes in the membrane potential of a cancer...

New Catalytic Reactive-Hydrogen Membranes Capture and Break Down PFAS

Researchers at Arizona State University (ASU) and collaborating institutions have developed catalytic reactive-hydrogen membranes that capture and chemically break down six per- and polyfluoroalkyl...

Diasome’s HDV-Insulin for T1D Finalizing Phase III Plans After Promising Data

Glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptor agonists have revolutionized the treatment of type 2 diabetes (T2D). None of these blockbuster...

New Catalytic Reactive-Hydrogen Membranes Capture and Break Down PFAS

Researchers at Arizona State University (ASU) and collaborating institutions have developed catalytic reactive-hydrogen membranes that capture and chemically break down six per- and polyfluoroalkyl...

Diasome’s HDV-Insulin for T1D Finalizing Phase III Plans After Promising Data

Glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptor agonists have revolutionized the treatment of type 2 diabetes (T2D). None of these blockbuster...

ADC Developmentfrom Concept to Clinic

Read Now Antibody-drug conjugates (ADCs) combine the specificity of monoclonal antibodies with the therapeutic activity of small molecule payloads, enabling targeted delivery...

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New Catalytic Reactive-Hydrogen Membranes Capture and Break Down PFAS

Researchers at Arizona State University (ASU) and collaborating institutions have developed catalytic reactive-hydrogen membranes that capture and chemically break down six per- and polyfluoroalkyl...

Diasome’s HDV-Insulin for T1D Finalizing Phase III Plans After Promising Data

Glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptor agonists have revolutionized the treatment of type 2 diabetes (T2D). None of these blockbuster...

ADC Developmentfrom Concept to Clinic

Read Now Antibody-drug conjugates (ADCs) combine the specificity of monoclonal antibodies with the therapeutic activity of small molecule payloads, enabling targeted delivery...